Research Centre Information Centre AgeFactDB
Release 1 - Aug 15, 2013

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Ageing Factors List - Experimental Evidence

NOTE:

Ageing phenotype observations are considered as experimental analysis. They confirm or reject the ageing relevance for particular ageing factor(s). For genes that are homologous to known ageing-relevant genes there is thus far no experimental evidence. They are considered as candidate genes.
Due to the different data structures of ageing phenotype observation data integrated from other databases we subdivide these observations into type 1 and 2. Observations of type 1 contain the phenotype data mostly unseparated within a single description. Observations of type 2 contain lifespan data in a more structured form (e.g.: separated into lifespan effect, lifespan change, lifespan value). Currently there might be an overlap between the observations of type 1 and 2 from the same source, namely GenAge. But we are working on a reduction of this overlap.

Ageing Relevance:
1 ... 100 [next icon]
# Name Type NCBI Gene ID Species Synonyms Ageing Relevance Analysis Ageing Factor Stable ID
1 1, 1-Dimethylbiguanide hydrochloride compound Mus musculus
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009127
2 14-3-3epsilon gene 42186 Drosophila melanogaster Gene Synonyms:
14-3-3 | 14-3-3 epsilon | 14-3-3&epsilon | 14-3-3-e | 14-3-3-epsilon | 14-3-30epsilon | 14-3-3e | 14-3-3EPSILON | 14-3-3epsilon | 14-3-3epsilon-PA | 14-3-3epsilon-PB | 14-3-3epsilon-PC | 14-3-3epsilon-PD | 14-3-3omicron | 1433epsilon | 143E_DROME | CG31196 | CG31196 gene product from transcript CG31196-RB | CG31196-PA | CG31196-PB | CG31196-PC | CG31196-PD | CT24092 | D14-3-3e | D14-3-3epsilon | d14-3-3epsilon | Dmel_CG31196 | DmelCG31196 | EK3-5 | eps | Epsilon | epsilon | l(3)j2B10 | PAR-5 | Par-5 | par-5 | PAR5 | SR3-9 | Su(Raf)3B | Suppressor of Ras85D 3-9 | suppressor of Ras85D 3-9 | Tyrosine-3-monooxygenase
Source: [GPSDB icon]GPSDB
Homology Analysis Data [putative][AgeFactDB Homology Analysis icon]AgeFactDB Homology Analysis
Ageing Phenotype Observation—Data Type 1[GenAge icon]GenAge
Ageing Phenotype Observation—Data Type 2[GenAge icon]GenAge
AF_000903
3 2,4-dinitrophenol compound Mus musculus
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009101
4 25-azacoprostane compound Caenorhabditis elegans
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009131
5 3,3-diethyl-2-pyrrolidinone compound Caenorhabditis elegans
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009093
6 3,5-Dihydroxy-4'-acetoxy-trans-stilbene compound Saccharomyces cerevisiae
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009104
7 3,5-Dihydroxy-4'-ethyl-trans-stilbene compound Saccharomyces cerevisiae
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009103
8 3,5-Dihydroxy-4'-thiomethyl-trans-stilbene compound Saccharomyces cerevisiae
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009102
9 3-O--d-glucopyranoside-(41)--d-glucopyranoside (Q3M) compound Caenorhabditis elegans
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009121
10 4,5,6,7-tetrabromo-benzimidazole compound Saccharomyces cerevisiae
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009081
11 4-HNE compound Caenorhabditis elegans
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009111
12 A2M gene 2 Homo sapiens Gene Synonyms:
A2M | A2MD | alpha-2-M | ALPHA-2-MACROGLOBULIN | alpha-2-macroglobulin | C3 and PZP-like alpha-2-macroglobulin domain-containing protein 5 | CPAMD5 | FWP007 | MACROGLOBULIN, ALPHA-2 | S863-7
Source: [GPSDB icon]GPSDB
Homology Analysis Data [putative][AgeFactDB Homology Analysis icon]AgeFactDB Homology Analysis
Ageing Phenotype Observation—Data Type 1[GenAge icon]GenAge
AF_002303
13 AAC3 gene 852380 Saccharomyces cerevisiae
Homology Analysis Data [putative][AgeFactDB Homology Analysis icon]AgeFactDB Homology Analysis
Ageing Phenotype Observation—Data Type 2[GenAge icon]GenAge
AF_009397
14 AAH1 gene 855581 Saccharomyces cerevisiae Gene Synonyms:
AAH1 | Aah1p | adenine deaminase | N1208 | N1825 | YNL141W
Source: [GPSDB icon]GPSDB
Homology Analysis Data [putative][AgeFactDB Homology Analysis icon]AgeFactDB Homology Analysis
Ageing Phenotype Observation—Data Type 2[GenAge icon]GenAge
AF_002448
15 aak-2 gene 181727 Caenorhabditis elegans Gene Synonyms:
aak-2 | CE07458 | CE31222 | CE31223 | CELE_T01C8.1 | Protein AAK-2 | T01C8.1 | T01C8.1a | T01C8.1b | T01C8.1c | T01C8.1c.1 | T01C8.1c.2 | T01C8.1c.3 | WP:CE07458 | WP:CE31222 | WP:CE31223
Source: [GPSDB icon]GPSDB
Homology Analysis Data [putative][AgeFactDB Homology Analysis icon]AgeFactDB Homology Analysis
Ageing Phenotype Observation—Data Type 1[GenAge icon]GenAge
[GenDR icon]GenDR
Ageing Phenotype Observation—Data Type 2[GenAge icon]GenAge
[Lifespan Observations Database icon]Lifespan Observations Database
[AgeFactDB Curator icon]AgeFactDB Curator
AF_005104
16 aakb-1 gene 181492 Caenorhabditis elegans Gene Synonyms:
aakb-1 | CELE_F55F3.1 | Protein AAKB-1
Source: [GPSDB icon]GPSDB
Homology Analysis Data [putative][AgeFactDB Homology Analysis icon]AgeFactDB Homology Analysis
Ageing Phenotype Observation—Data Type 1[GenAge icon]GenAge
Ageing Phenotype Observation—Data Type 2[GenAge icon]GenAge
AF_006708
17 aakb-2 gene 176552 Caenorhabditis elegans Gene Synonyms:
aakb-2 | CELE_Y47D3A.15 | Protein AAKB-2
Source: [GPSDB icon]GPSDB
Homology Analysis Data [putative][AgeFactDB Homology Analysis icon]AgeFactDB Homology Analysis
Ageing Phenotype Observation—Data Type 1[GenAge icon]GenAge
Ageing Phenotype Observation—Data Type 2[GenAge icon]GenAge
AF_007183
18 aakg-2 gene 181736 Caenorhabditis elegans Gene Synonyms:
aakg-2 | CELE_T20F7.6 | Protein AAKG-2
Source: [GPSDB icon]GPSDB
Homology Analysis Data [putative][AgeFactDB Homology Analysis icon]AgeFactDB Homology Analysis
Ageing Phenotype Observation—Data Type 1[GenDR icon]GenDR
AF_007009
19 aap-1 gene 172141 Caenorhabditis elegans Gene Synonyms:
aap-1 | CELE_Y110A7A.10 | Protein AAP-1
Source: [GPSDB icon]GPSDB
Homology Analysis Data [putative][AgeFactDB Homology Analysis icon]AgeFactDB Homology Analysis
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_007107
20 aat-8 gene 185079 Caenorhabditis elegans Gene Synonyms:
aat-8 | CELE_F28F9.4 | Protein AAT-8
Source: [GPSDB icon]GPSDB
Homology Analysis Data [putative][AgeFactDB Homology Analysis icon]AgeFactDB Homology Analysis
Ageing Phenotype Observation—Data Type 2[GenAge icon]GenAge
[Lifespan Observations Database icon]Lifespan Observations Database
AF_006568
21 AAT1 gene 853755 Saccharomyces cerevisiae Gene Synonyms:
AAT1 | Aat1p | aspartate transaminase AAT1 | YKL106W | YKL461
Source: [GPSDB icon]GPSDB
Homology Analysis Data [putative][AgeFactDB Homology Analysis icon]AgeFactDB Homology Analysis
Ageing Phenotype Observation—Data Type 1[GenDR icon]GenDR
Ageing Phenotype Observation—Data Type 2[GenAge icon]GenAge
AF_002474
22 AAT2 gene 850714 Saccharomyces cerevisiae Gene Synonyms:
AAT2 | Aat2p | ASP5 | aspartate transaminase AAT2 | L1746 | YLR027C
Source: [GPSDB icon]GPSDB
Homology Analysis Data [putative][AgeFactDB Homology Analysis icon]AgeFactDB Homology Analysis
Ageing Phenotype Observation—Data Type 2[GenAge icon]GenAge
AF_002475
23 abc1 gene Saccharomyces cerevisiae
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_008822
24 abcx-1 gene 183860 Caenorhabditis elegans Gene Synonyms:
abcx-1 | CELE_C56E6.1 | Protein ABCX-1
Source: [GPSDB icon]GPSDB
Ageing Phenotype Observation—Data Type 2[GenAge icon]GenAge
AF_006442
25 ABL1 gene 25 Homo sapiens Gene Synonyms:
ABELSON MURINE LEUKEMIA VIRAL ONCOGENE HOMOLOG 1 | ABELSON STRAIN OF MURINE LEUKEMIA VIRUS | Abelson tyrosine-protein kinase 1 | ABL | ABL1 | bcr/abl | bcr/c-abl oncogene protein | c-ABL | c-abl oncogene 1, non-receptor tyrosine kinase | c-abl oncogene 1, receptor tyrosine kinase | JTK7 | p150 | proto-oncogene c-Abl | proto-oncogene tyrosine-protein kinase ABL1 | RP11-83J21.1 | TRANSFORMATION GENE: ONCOGENE ABL | tyrosine-protein kinase ABL1 | v-abl | v-abl Abelson murine leukemia viral oncogene homolog 1
Source: [GPSDB icon]GPSDB
Homology Analysis Data [putative][AgeFactDB Homology Analysis icon]AgeFactDB Homology Analysis
Ageing Phenotype Observation—Data Type 1[GenAge icon]GenAge
AF_002554
26 ABP1 gene 850450 Saccharomyces cerevisiae Gene Synonyms:
ABP1 | Abp1p | YCR088W | YCR88W
Source: [GPSDB icon]GPSDB
Homology Analysis Data [putative][AgeFactDB Homology Analysis icon]AgeFactDB Homology Analysis
Ageing Phenotype Observation—Data Type 2[GenAge icon]GenAge
AF_002624
27 abtm-1 gene 171807 Caenorhabditis elegans Gene Synonyms:
abtm-1 | CELE_Y74C10AR.3 | Protein ABTM-1
Source: [GPSDB icon]GPSDB
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_007278
28 abu-11 gene 173404 Caenorhabditis elegans Gene Synonyms:
abu-11 | CELE_T01D1.6 | Protein ABU-11
Source: [GPSDB icon]GPSDB
Homology Analysis Data [putative][AgeFactDB Homology Analysis icon]AgeFactDB Homology Analysis
Ageing Phenotype Observation—Data Type 2[GenAge icon]GenAge
[Lifespan Observations Database icon]Lifespan Observations Database
AF_006926
29 ACB1 gene 852925 Saccharomyces cerevisiae
Homology Analysis Data [putative][AgeFactDB Homology Analysis icon]AgeFactDB Homology Analysis
Ageing Phenotype Observation—Data Type 2[GenAge icon]GenAge
AF_009379
30 acdh-13 gene 177654 Caenorhabditis elegans Gene Synonyms:
acdh-13 | CELE_C28C12.9 | Protein ACDH-13
Source: [GPSDB icon]GPSDB
Ageing Phenotype Observation—Data Type 2[GenAge icon]GenAge
AF_006360
31 ace-1 gene 181706 Caenorhabditis elegans Gene Synonyms:
ace-1 | ACE1 | CE07569 | CELE_W09B12.1 | Protein ACE-1 | W09B12.1 | W09B12.1.1 | W09B12.1.2 | WP:CE07569
Source: [GPSDB icon]GPSDB
Homology Analysis Data [putative][AgeFactDB Homology Analysis icon]AgeFactDB Homology Analysis
Ageing Phenotype Observation—Data Type 2[GenAge icon]GenAge
AF_002780
32 Acetic acid compound Saccharomyces cerevisiae
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009068
33 acl-11 gene 185044 Caenorhabditis elegans Gene Synonyms:
acl-11 | CELE_F28B3.9 | Protein ACL-11
Source: [GPSDB icon]GPSDB
Homology Analysis Data [putative][AgeFactDB Homology Analysis icon]AgeFactDB Homology Analysis
Ageing Phenotype Observation—Data Type 2[GenAge icon]GenAge
[Lifespan Observations Database icon]Lifespan Observations Database
AF_006566
34 aco-2 gene 176121 Caenorhabditis elegans Gene Synonyms:
aco-2 | CE25005 | CE30144 | CE32436 | CELE_F54H12.1 | F54H12.1 | F54H12.1a | F54H12.1b | F54H12.1c | F54H12.1c.1 | F54H12.1c.2 | F54H12.1c.3 | Protein ACO-2 | WP:CE25005 | WP:CE30144 | WP:CE32436
Source: [GPSDB icon]GPSDB
Homology Analysis Data [putative][AgeFactDB Homology Analysis icon]AgeFactDB Homology Analysis
Ageing Phenotype Observation—Data Type 1[GenAge icon]GenAge
Ageing Phenotype Observation—Data Type 2[GenAge icon]GenAge
[Lifespan Observations Database icon]Lifespan Observations Database
AF_005673
35 ACO2 gene 853230 Saccharomyces cerevisiae Gene Synonyms:
ACO2 | Aco2p | aconitate hydratase ACO2 | J0327 | YJL200C
Source: [GPSDB icon]GPSDB
Homology Analysis Data [putative][AgeFactDB Homology Analysis icon]AgeFactDB Homology Analysis
Ageing Phenotype Observation—Data Type 2[GenAge icon]GenAge
AF_002850
36 acs-14 gene 176785 Caenorhabditis elegans Gene Synonyms:
Possible synonym group : acs-14 | CE05585 | F11A3.1 | F11A3.1.1 | F11A3.1.2 | WP:CE05585
Source: [GPSDB icon]GPSDB
Ageing Phenotype Observation—Data Type 2[GenAge icon]GenAge
AF_009253
37 acs-7 gene 174472 Caenorhabditis elegans Gene Synonyms:
acs-7 | CELE_C01G6.7 | Protein ACS-7
Source: [GPSDB icon]GPSDB
Ageing Phenotype Observation—Data Type 2[GenAge icon]GenAge
AF_006302
38 ACS2 gene 850846 Saccharomyces cerevisiae Gene Synonyms:
acetate--CoA ligase ACS2 | ACS2 | Acs2p | L9634.10 | YLR153C
Source: [GPSDB icon]GPSDB
Homology Analysis Data [putative][AgeFactDB Homology Analysis icon]AgeFactDB Homology Analysis
Ageing Phenotype Observation—Data Type 2[GenAge icon]GenAge
AF_002888
39 ada-2 gene 174194 Caenorhabditis elegans Gene Synonyms:
ada-2 | CELE_F32A5.1 | Protein ADA-2
Source: [GPSDB icon]GPSDB
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_006572
40 ADA1 gene 855821 Saccharomyces cerevisiae Gene Synonyms:
ADA1 | GAN1 | HFI1 | Hfi1p | SRM12 | SUP110 | YPL254W
Source: [GPSDB icon]GPSDB
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_002949
41 ADA2 gene 852059 Saccharomyces cerevisiae
Homology Analysis Data [putative][AgeFactDB Homology Analysis icon]AgeFactDB Homology Analysis
Ageing Phenotype Observation—Data Type 2[GenAge icon]GenAge
AF_009323
42 ADCY5 gene 111 Homo sapiens Gene Synonyms:
AC5 | ADCY5 | ADENYLATE CYCLASE 5 | adenylate cyclase 5 | adenylate cyclase type 5 | adenylate cyclase type V | ADENYLYL CYCLASE 5 | adenylyl cyclase 5 | ATP pyrophosphate-lyase 5 | FDFM
Source: [GPSDB icon]GPSDB
Homology Analysis Data [putative][AgeFactDB Homology Analysis icon]AgeFactDB Homology Analysis
Ageing Phenotype Observation—Data Type 1[GenAge icon]GenAge
AF_002721
43 Adcy5 gene 224129 Mus musculus Gene Synonyms:
AC5 | Ac5 | Adcy5 | adenylate cyclase 5 | adenylate cyclase type 5 | adenylate cyclase type V | adenylyl cyclase 5 | ATP pyrophosphate-lyase 5
Source: [GPSDB icon]GPSDB
Homology Analysis Data [putative][AgeFactDB Homology Analysis icon]AgeFactDB Homology Analysis
Ageing Phenotype Observation—Data Type 1[GenAge icon]GenAge
Ageing Phenotype Observation—Data Type 2[GenAge icon]GenAge
[Lifespan Observations Database icon]Lifespan Observations Database
AF_002732
44 ADD37 gene 855222 Saccharomyces cerevisiae Gene Synonyms:
ADD37 | Add37p | YM8010.14 | YMR184W
Source: [GPSDB icon]GPSDB
Homology Analysis Data [putative][AgeFactDB Homology Analysis icon]AgeFactDB Homology Analysis
Ageing Phenotype Observation—Data Type 2[GenAge icon]GenAge
AF_002956
45 ADD66 gene 853629 Saccharomyces cerevisiae Gene Synonyms:
ADD66 | Add66p | PBA2 | POC2 | YKL206C
Source: [GPSDB icon]GPSDB
Homology Analysis Data [putative][AgeFactDB Homology Analysis icon]AgeFactDB Homology Analysis
Ageing Phenotype Observation—Data Type 2[GenAge icon]GenAge
AF_002957
46 ADE1 gene 851272 Saccharomyces cerevisiae Gene Synonyms:
ADE1 | Ade1p | phosphoribosylaminoimidazolesuccinocarboxamide synthase | YAR015W
Source: [GPSDB icon]GPSDB
Homology Analysis Data [putative][AgeFactDB Homology Analysis icon]AgeFactDB Homology Analysis
Ageing Phenotype Observation—Data Type 2[GenAge icon]GenAge
AF_002960
47 ADE12 gene 855501 Saccharomyces cerevisiae Gene Synonyms:
ADE12 | Ade12p | adenylosuccinate synthase | BRA9 | N1290 | YNL220W
Source: [GPSDB icon]GPSDB
Homology Analysis Data [putative][AgeFactDB Homology Analysis icon]AgeFactDB Homology Analysis
Ageing Phenotype Observation—Data Type 2[GenAge icon]GenAge
AF_002958
48 ADE17 gene 855149 Saccharomyces cerevisiae Gene Synonyms:
ADE17 | Ade17p | bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase ADE17 | YM8564.02C | YMR120C
Source: [GPSDB icon]GPSDB
Homology Analysis Data [putative][AgeFactDB Homology Analysis icon]AgeFactDB Homology Analysis
Ageing Phenotype Observation—Data Type 2[GenAge icon]GenAge
AF_002959
49 ADE2 gene 854295 Saccharomyces cerevisiae
Homology Analysis Data [putative][AgeFactDB Homology Analysis icon]AgeFactDB Homology Analysis
Ageing Phenotype Observation—Data Type 2[GenAge icon]GenAge
AF_009331
50 ADE3 gene 853118 Saccharomyces cerevisiae
Homology Analysis Data [putative][AgeFactDB Homology Analysis icon]AgeFactDB Homology Analysis
Ageing Phenotype Observation—Data Type 2[GenAge icon]GenAge
AF_009284
51 ADE4 gene 855346 Saccharomyces cerevisiae Gene Synonyms:
ADE4 | Ade4p | amidophosphoribosyltransferase | YM9952.02C | YMR300C
Source: [GPSDB icon]GPSDB
Homology Analysis Data [putative][AgeFactDB Homology Analysis icon]AgeFactDB Homology Analysis
Ageing Phenotype Observation—Data Type 1[GenDR icon]GenDR
Ageing Phenotype Observation—Data Type 2[GenAge icon]GenAge
AF_002961
52 ADE5,7 gene 852617 Saccharomyces cerevisiae
Homology Analysis Data [putative][AgeFactDB Homology Analysis icon]AgeFactDB Homology Analysis
Ageing Phenotype Observation—Data Type 2[GenAge icon]GenAge
AF_009332
53 ADE6 gene 852952 Saccharomyces cerevisiae Gene Synonyms:
ADE6 | Ade6p | phosphoribosylformylglycinamidine synthase | YGR061C
Source: [GPSDB icon]GPSDB
Homology Analysis Data [putative][AgeFactDB Homology Analysis icon]AgeFactDB Homology Analysis
Ageing Phenotype Observation—Data Type 2[GenAge icon]GenAge
AF_002962
54 ADH1 gene 854068 Saccharomyces cerevisiae Gene Synonyms:
ADC1 | ADH1 | Adh1p | alcohol dehydrogenase ADH1 | O0947 | YOL086C
Source: [GPSDB icon]GPSDB
Homology Analysis Data [putative][AgeFactDB Homology Analysis icon]AgeFactDB Homology Analysis
Ageing Phenotype Observation—Data Type 2[GenAge icon]GenAge
[Lifespan Observations Database icon]Lifespan Observations Database
AF_002953
55 ADH2 gene 855349 Saccharomyces cerevisiae Gene Synonyms:
ADH2 | Adh2p | ADR2 | alcohol dehydrogenase ADH2 | YM9952.05C | YMR303C
Source: [GPSDB icon]GPSDB
Homology Analysis Data [putative][AgeFactDB Homology Analysis icon]AgeFactDB Homology Analysis
Ageing Phenotype Observation—Data Type 2[GenAge icon]GenAge
AF_002968
56 ADK1 gene 851812 Saccharomyces cerevisiae Gene Synonyms:
adenylate kinase ADK1 | ADK1 | Adk1p | AKY | AKY1 | AKY2 | YD9934.11 | YDR226W
Source: [GPSDB icon]GPSDB
Homology Analysis Data [putative][AgeFactDB Homology Analysis icon]AgeFactDB Homology Analysis
Ageing Phenotype Observation—Data Type 2[GenAge icon]GenAge
AF_002974
57 adr-1 gene 172542 Caenorhabditis elegans Gene Synonyms:
adr-1 | CELE_H15N14.1 | Protein ADR-1
Source: [GPSDB icon]GPSDB
Homology Analysis Data [putative][AgeFactDB Homology Analysis icon]AgeFactDB Homology Analysis
Ageing Phenotype Observation—Data Type 2[GenAge icon]GenAge
AF_006777
58 adr-2 gene 176022 Caenorhabditis elegans Gene Synonyms:
adr-2 | CE25120 | CELE_T20H4.4 | Protein ADR-2 | T20H4.4 | T20H4.4.1 | T20H4.4.2 | WP:CE25120
Source: [GPSDB icon]GPSDB
Homology Analysis Data [putative][AgeFactDB Homology Analysis icon]AgeFactDB Homology Analysis
Ageing Phenotype Observation—Data Type 2[GenAge icon]GenAge
AF_005689
59 ADR1 gene 851802 Saccharomyces cerevisiae
Homology Analysis Data [putative][AgeFactDB Homology Analysis icon]AgeFactDB Homology Analysis
Ageing Phenotype Observation—Data Type 2[GenAge icon]GenAge
AF_009407
60 AEP1 gene 855086 Saccharomyces cerevisiae Gene Synonyms:
AEP1 | Aep1p | NCA1 | YM9916.03 | YMR064W
Source: [GPSDB icon]GPSDB
Homology Analysis Data [putative][AgeFactDB Homology Analysis icon]AgeFactDB Homology Analysis
Ageing Phenotype Observation—Data Type 2[GenAge icon]GenAge
AF_003004
61 aex-3 gene 180420 Caenorhabditis elegans Gene Synonyms:
aex-3 | C02H7.3 | C02H7.3a | C02H7.3b | CE16806 | CE30850 | CELE_C02H7.3 | Protein AEX-3 | WP:CE16806 | WP:CE30850
Source: [GPSDB icon]GPSDB
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_004219
62 AFG3 gene 856737 Saccharomyces cerevisiae Gene Synonyms:
AAA family ATPase AFG3 | AFG3 | Afg3p | YER017C | YTA10
Source: [GPSDB icon]GPSDB
Homology Analysis Data [putative][AgeFactDB Homology Analysis icon]AgeFactDB Homology Analysis
Ageing Phenotype Observation—Data Type 2[GenAge icon]GenAge
[Lifespan Observations Database icon]Lifespan Observations Database
AF_002369
63 Agar barrier other ageing factor Caenorhabditis elegans
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009167
64 AGC1 gene 856132 Saccharomyces cerevisiae Gene Synonyms:
AGC1 | Agc1p | YP9367.01C | YPR021C
Source: [GPSDB icon]GPSDB
Homology Analysis Data [putative][AgeFactDB Homology Analysis icon]AgeFactDB Homology Analysis
Ageing Phenotype Observation—Data Type 2[GenAge icon]GenAge
AF_003019
65 age-1 gene 174762 Caenorhabditis elegans Gene Synonyms:
age-1 | B0334.8 | CE43431 | CELE_B0334.8 | daf-23 | Protein AGE-1 | WP:CE43431
Source: [GPSDB icon]GPSDB
Homology Analysis Data [putative][AgeFactDB Homology Analysis icon]AgeFactDB Homology Analysis
Ageing Phenotype Observation—Data Type 1[GenAge icon]GenAge
[GenDR icon]GenDR
Ageing Phenotype Observation—Data Type 2[GenAge icon]GenAge
[Lifespan Observations Database icon]Lifespan Observations Database
[AgeFactDB Curator icon]AgeFactDB Curator
AF_003959
66 age-2 gene Caenorhabditis elegans
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_008686
67 agl-1 gene 175091 Caenorhabditis elegans
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009012
68 AGP1 gene 850333 Saccharomyces cerevisiae Gene Synonyms:
AGP1 | Agp1p | YCC5 | YCL025C | YCL25C
Source: [GPSDB icon]GPSDB
Homology Analysis Data [putative][AgeFactDB Homology Analysis icon]AgeFactDB Homology Analysis
Ageing Phenotype Observation—Data Type 2[GenAge icon]GenAge
[Lifespan Observations Database icon]Lifespan Observations Database
AF_003049
69 AGPAT2 gene 10555 Homo sapiens Gene Synonyms:
1-acyl-sn-glycerol-3-phosphate acyltransferase beta | 1-ACYLGLYCEROL-3-PHOSPHATE O-ACYLTRANSFERASE 2 | 1-acylglycerol-3-phosphate O-acyltransferase 2 | 1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta) | 1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase-beta) | 1-AGP acyltransferase 2 | 1-AGPAT 2 | 1-AGPAT2 | AGPAT2 | Berardinelli-Seip congenital lipodystrophy | BSCL | BSCL1 | LPAAB | LPAAT-BETA | LPAAT-beta | lysophosphatidic acid acyltransferase beta | lysophosphatidic acid acyltransferase, beta | LYSOPHOSPHATIDIC ACID ACYLTRANSFERASE-BETA | lysophosphatidic acid acyltransferase-beta
Source: [GPSDB icon]GPSDB
Homology Analysis Data [putative][AgeFactDB Homology Analysis icon]AgeFactDB Homology Analysis
Ageing Phenotype Observation—Data Type 1[GenAge icon]GenAge
AF_001969
70 AGTR1 gene 185 Homo sapiens Gene Synonyms:
AG2S | AGTR1 | AGTR1A | AGTR1B | angiotensin II receptor, type 1 | ANGIOTENSIN II RECEPTOR, VASCULAR TYPE 1 | ANGIOTENSIN RECEPTOR 1 | ANGIOTENSIN RECEPTOR 1A | angiotensin receptor 1B | AT1 | AT1AR | AT1B | AT1BR | AT1R | AT2R1 | AT2R1A | AT2R1B | HAT1R | type-1 angiotensin II receptor | type-1B angiotensin II receptor
Source: [GPSDB icon]GPSDB
Homology Analysis Data [putative][AgeFactDB Homology Analysis icon]AgeFactDB Homology Analysis
Ageing Phenotype Observation—Data Type 1[GenAge icon]GenAge
AF_003017
71 Agtr1a gene 11607 Mus musculus Gene Synonyms:
AG2S | Agtr-1a | Agtr1 | Agtr1a | angiotensin II receptor, type 1a | angiotensin II type-1A receptor | angiotensin receptor 1 | angiotensin receptor 1a | Angtr-1a | AT1 | AT1a | AT2R1 | AT2R1A | type-1A angiotensin II receptor
Source: [GPSDB icon]GPSDB
Homology Analysis Data [putative][AgeFactDB Homology Analysis icon]AgeFactDB Homology Analysis
Ageing Phenotype Observation—Data Type 2[GenAge icon]GenAge
AF_003018
72 AIFM1 gene 9131 Homo sapiens Gene Synonyms:
AIF | AIFM1 | APOPTOSIS-INDUCING FACTOR | apoptosis-inducing factor 1, mitochondrial | APOPTOSIS-INDUCING FACTOR, MITOCHONDRION-ASSOCIATED, 1 | apoptosis-inducing factor, mitochondrion-associated, 1 | CMTX4 | COWCK | COXPD6 | PDCD8 | PROGRAMMED CELL DEATH 8 | programmed cell death 8 (apoptosis-inducing factor) | RP3-438D16.2 | striatal apoptosis-inducing factor
Source: [GPSDB icon]GPSDB
Homology Analysis Data [putative][AgeFactDB Homology Analysis icon]AgeFactDB Homology Analysis
Ageing Phenotype Observation—Data Type 1[GenAge icon]GenAge
AF_003057
73 AIM24 gene 853543 Saccharomyces cerevisiae Gene Synonyms:
AIM24 | Aim24p | FMP26 | J1847 | YJR080C
Source: [GPSDB icon]GPSDB
Homology Analysis Data [putative][AgeFactDB Homology Analysis icon]AgeFactDB Homology Analysis
Ageing Phenotype Observation—Data Type 2[GenAge icon]GenAge
AF_003059
74 AIM36 gene 855189 Saccharomyces cerevisiae Gene Synonyms:
AIM36 | Aim36p | FMP39 | YM8520.06C | YMR157C
Source: [GPSDB icon]GPSDB
Homology Analysis Data [putative][AgeFactDB Homology Analysis icon]AgeFactDB Homology Analysis
Ageing Phenotype Observation—Data Type 2[GenAge icon]GenAge
AF_003061
75 AIM4 gene 852493 Saccharomyces cerevisiae Gene Synonyms:

Possible synonym group 1: AIM4 | C1Q_00687 | SOY1
Source: [GPSDB icon]GPSDB

Possible synonym group 2: AIM4 | EC1118_1B15_3598g | SOY1
Source: [GPSDB icon]GPSDB

Possible synonym group 3: AIM4 | SCRG_02777 | SOY1
Source: [GPSDB icon]GPSDB

Possible synonym group 4: AIM4 | SCY_0404 | SOY1
Source: [GPSDB icon]GPSDB

Ageing Phenotype Observation—Data Type 1[GenDR icon]GenDR
AF_009461
76 AIMP3 gene Mus musculus
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_008902
77 ain-1 gene 181719 Caenorhabditis elegans Gene Synonyms:
ain-1 | CELE_C06G1.4 | Protein AIN-1
Source: [GPSDB icon]GPSDB
Homology Analysis Data [putative][AgeFactDB Homology Analysis icon]AgeFactDB Homology Analysis
Ageing Phenotype Observation—Data Type 1[GenAge icon]GenAge
Ageing Phenotype Observation—Data Type 2[GenAge icon]GenAge
[Lifespan Observations Database icon]Lifespan Observations Database
AF_006323
78 aip-1 gene 179898 Caenorhabditis elegans Gene Synonyms:
aip-1 | CELE_F58E10.4 | Protein AIP-1
Source: [GPSDB icon]GPSDB
Homology Analysis Data [putative][AgeFactDB Homology Analysis icon]AgeFactDB Homology Analysis
Ageing Phenotype Observation—Data Type 2[GenAge icon]GenAge
AF_006740
79 Akh gene 38495 Drosophila melanogaster Gene Synonyms:
adipo- kinetic hormone | Adipokinetic hormone | adipokinetic hormone | Adipokinetic hormone-like | adipokinetic hormone-like | AKH | Akh | akh | Akh-PA | CG1171 | CG1171-PA | dAkh | Dmel_CG1171 | DmelCG1171 | Drm-AKH | Hrth | Hypertrehaloseaemic-hormone
Source: [GPSDB icon]GPSDB
Ageing Phenotype Observation—Data Type 1[GenDR icon]GenDR
AF_003073
80 AKL1 gene 852351 Saccharomyces cerevisiae Gene Synonyms:
AKL1 | Akl1p | YBR0519 | YBR059C
Source: [GPSDB icon]GPSDB
Homology Analysis Data [putative][AgeFactDB Homology Analysis icon]AgeFactDB Homology Analysis
Ageing Phenotype Observation—Data Type 2[GenAge icon]GenAge
AF_003075
81 AKR1 gene 851857 Saccharomyces cerevisiae Gene Synonyms:
AKR1 | Akr1p | D9954.9 | YD9230B.03C | YDR264C
Source: [GPSDB icon]GPSDB
Homology Analysis Data [putative][AgeFactDB Homology Analysis icon]AgeFactDB Homology Analysis
Ageing Phenotype Observation—Data Type 2[GenAge icon]GenAge
AF_003076
82 Akt gene Anopheles stephensi
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009054
83 akt-1 gene 179424 Caenorhabditis elegans Gene Synonyms:
akt-1 | akt-1a | akt-1b | C12D8.10 | C12D8.10a | C12D8.10b | C12D8.10b.1 | C12D8.10b.2 | C12D8.10c | CE05274 | CE15612 | CE31304 | CELE_C12D8.10 | Protein AKT-1 | WP:CE05274 | WP:CE15612 | WP:CE31304
Source: [GPSDB icon]GPSDB
Homology Analysis Data [putative][AgeFactDB Homology Analysis icon]AgeFactDB Homology Analysis
Ageing Phenotype Observation—Data Type 2[GenAge icon]GenAge
[Lifespan Observations Database icon]Lifespan Observations Database
AF_004296
84 akt-2 gene 181524 Caenorhabditis elegans Gene Synonyms:
akt-2 | CE18646 | CE29298 | CELE_F28H6.1 | F28H6.1 | F28H6.1a | F28H6.1b | Protein AKT-2 | WP:CE18646 | WP:CE29298
Source: [GPSDB icon]GPSDB
Homology Analysis Data [putative][AgeFactDB Homology Analysis icon]AgeFactDB Homology Analysis
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_005425
85 Akt1 gene 41957 Drosophila melanogaster
Homology Analysis Data [putative][AgeFactDB Homology Analysis icon]AgeFactDB Homology Analysis
Ageing Phenotype Observation—Data Type 1[GenAge icon]GenAge
Ageing Phenotype Observation—Data Type 2[GenAge icon]GenAge
AF_009258
86 AKT1 gene 207 Homo sapiens Gene Synonyms:
AKT | AKT1 | ONCOGENE AKT1 | PKB | PKB alpha | PKB-ALPHA | PRKBA | protein kinase B alpha | PROTEIN KINASE B-ALPHA | proto-oncogene c-Akt | RAC | rac protein kinase alpha | RAC SERINE/THREONINE PROTEIN KINASE | RAC-ALPHA | RAC-alpha serine/threonine-protein kinase | RAC-PK-alpha | V-AKT MURINE THYMOMA VIRAL ONCOGENE HOMOLOG 1 | v-akt murine thymoma viral oncogene homolog 1
Source: [GPSDB icon]GPSDB
Homology Analysis Data [putative][AgeFactDB Homology Analysis icon]AgeFactDB Homology Analysis
Ageing Phenotype Observation—Data Type 1[GenAge icon]GenAge
AF_003080
87 ALD3 gene 855205 Saccharomyces cerevisiae Gene Synonyms:
ALD3 | Ald3p | ALD4 | aldehyde dehydrogenase (NAD(+)) ALD3 | YM8520.18C | YMR169C
Source: [GPSDB icon]GPSDB
Homology Analysis Data [putative][AgeFactDB Homology Analysis icon]AgeFactDB Homology Analysis
Ageing Phenotype Observation—Data Type 2[GenAge icon]GenAge
AF_003083
88 ALD4 gene 854556 Saccharomyces cerevisiae Gene Synonyms:
ALD4 | Ald4p | ALD7 | aldehyde dehydrogenase (NADP(+)) ALD4 | ALDH2 | O6730 | YOR374W
Source: [GPSDB icon]GPSDB
Homology Analysis Data [putative][AgeFactDB Homology Analysis icon]AgeFactDB Homology Analysis
Ageing Phenotype Observation—Data Type 2[GenAge icon]GenAge
AF_003085
89 aldo-1 gene 176788 Caenorhabditis elegans
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009011
90 alg-2 gene 173468 Caenorhabditis elegans Gene Synonyms:
alg-2 | CELE_T07D3.7 | Protein ALG-2
Source: [GPSDB icon]GPSDB
Homology Analysis Data [putative][AgeFactDB Homology Analysis icon]AgeFactDB Homology Analysis
Ageing Phenotype Observation—Data Type 1[GenAge icon]GenAge
Ageing Phenotype Observation—Data Type 2[GenAge icon]GenAge
[Lifespan Observations Database icon]Lifespan Observations Database
AF_006963
91 ALG12 gene 855764 Saccharomyces cerevisiae Gene Synonyms:
ALG12 | Alg12p | dolichyl-P-Man:Man(7)GlcNAc(2)-PP-dolichol alpha-1,6-mannosyltransferase | ECM39 | N3265 | YNR030W
Source: [GPSDB icon]GPSDB
Homology Analysis Data [putative][AgeFactDB Homology Analysis icon]AgeFactDB Homology Analysis
Ageing Phenotype Observation—Data Type 2[GenAge icon]GenAge
[Lifespan Observations Database icon]Lifespan Observations Database
AF_003091
92 ALG5 gene 855874 Saccharomyces cerevisiae Gene Synonyms:
ALG5 | Alg5p | dolichyl-phosphate beta-glucosyltransferase | P1437 | YPL227C
Source: [GPSDB icon]GPSDB
Homology Analysis Data [putative][AgeFactDB Homology Analysis icon]AgeFactDB Homology Analysis
Ageing Phenotype Observation—Data Type 2[GenAge icon]GenAge
AF_003092
93 Alpha factor arrest other ageing factor Saccharomyces cerevisiae
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009155
94 Alpha, beta-trehalose compound Caenorhabditis elegans
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009083
95 Alpha-ketoglutarate compound Caenorhabditis elegans
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009139
96 alpha-Man-I gene 31957 Drosophila melanogaster Gene Synonyms:
alpha 1,2 mannosidase | alpha Mannosidase I | alpha mannosidase I | alpha-1,2-mannosidase I | alpha-D-mannosidase | ALPHA-MAN-1 | alpha-Man-I | alpha-Man-I-PH | alpha-Man-I-PI | alpha-Man-I-PJ | alpha-Man-I-PK | alpha-Man-I-PL | alpha-Man-I-PM | alpha-Man-I-PN | alpha-Man-I-PO | alpha-Man-I-PP | alpha-Man-l | alpha-mannosidase | CG17809 | CG18799 | CG32682 | CG32684 | CG42275 | CG42275-PH | CG42275-PI | CG42275-PJ | CG42275-PK | CG42275-PL | CG42275-PM | CG42275-PN | CG42275-PO | CG42275-PP | DM-GI | Dmel_CG32682 | Dmel_CG32684 | Dmel_CG42275 | DmelCG42275 | MA12 | Man'ase | MAN-1 | Mannosidase 1 | mannosidase 1 | mas-1 | mas1
Source: [GPSDB icon]GPSDB
Homology Analysis Data [putative][AgeFactDB Homology Analysis icon]AgeFactDB Homology Analysis
Ageing Phenotype Observation—Data Type 1[GenAge icon]GenAge
Ageing Phenotype Observation—Data Type 2[GenAge icon]GenAge
AF_003101
97 ALT2 gene 851690 Saccharomyces cerevisiae Gene Synonyms:
alanine transaminase ALT2 | ALT2 | Alt2p | YD9727.07C | YDR111C
Source: [GPSDB icon]GPSDB
Homology Analysis Data [putative][AgeFactDB Homology Analysis icon]AgeFactDB Homology Analysis
Ageing Phenotype Observation—Data Type 2[GenAge icon]GenAge
AF_003106
98 Alternative carbon source other ageing factor Saccharomyces cerevisiae
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009183
99 AMD1 gene 854973 Saccharomyces cerevisiae Gene Synonyms:
AMD | AMD1 | Amd1p | AMD3 | AMP deaminase | YML035C
Source: [GPSDB icon]GPSDB
Homology Analysis Data [putative][AgeFactDB Homology Analysis icon]AgeFactDB Homology Analysis
Ageing Phenotype Observation—Data Type 2[GenAge icon]GenAge
AF_003108
100 AMN1 gene 852455 Saccharomyces cerevisiae Gene Synonyms:
AMN1 | Amn1p | CST13 | ICS4 | YBR1208 | YBR158W
Source: [GPSDB icon]GPSDB
Homology Analysis Data [putative][AgeFactDB Homology Analysis icon]AgeFactDB Homology Analysis
Ageing Phenotype Observation—Data Type 2[GenAge icon]GenAge
AF_003113