Research Centre Information Centre AgeFactDB
Release 1 - Aug 15, 2013

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Compounds List

NOTE:

Ageing phenotype observations are considered as experimental analysis. They confirm or reject the ageing relevance for particular ageing factor(s). For genes that are homologous to known ageing-relevant genes there is thus far no experimental evidence. They are considered as candidate genes.
Due to the different data structures of ageing phenotype observation data integrated from other databases we subdivide these observations into type 1 and 2. Observations of type 1 contain the phenotype data mostly unseparated within a single description. Observations of type 2 contain lifespan data in a more structured form (e.g.: separated into lifespan effect, lifespan change, lifespan value). Currently there might be an overlap between the observations of type 1 and 2 from the same source, namely GenAge. But we are working on a reduction of this overlap.

Ageing Relevance:
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# Compound Name Species Ageing Relevance Analysis Ageing Factor Stable ID
1 1, 1-Dimethylbiguanide hydrochloride Mus musculus
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009127
2 2,4-dinitrophenol Mus musculus
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009101
3 25-azacoprostane Caenorhabditis elegans
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009131
4 3,3-diethyl-2-pyrrolidinone Caenorhabditis elegans
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009093
5 3,5-Dihydroxy-4'-acetoxy-trans-stilbene Saccharomyces cerevisiae
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009104
6 3,5-Dihydroxy-4'-ethyl-trans-stilbene Saccharomyces cerevisiae
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009103
7 3,5-Dihydroxy-4'-thiomethyl-trans-stilbene Saccharomyces cerevisiae
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009102
8 3-O--d-glucopyranoside-(41)--d-glucopyranoside (Q3M) Caenorhabditis elegans
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009121
9 4,5,6,7-tetrabromo-benzimidazole Saccharomyces cerevisiae
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009081
10 4-HNE Caenorhabditis elegans
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009111
11 Acetic acid Saccharomyces cerevisiae
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009068
12 Alpha, beta-trehalose Caenorhabditis elegans
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009083
13 Alpha-ketoglutarate Caenorhabditis elegans
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009139
14 Ampicillin Caenorhabditis elegans
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009109
15 Antimycin a Saccharomyces cerevisiae
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009065
16 Ascorbic acid Caenorhabditis elegans
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009112
17 Ascr#2 Caenorhabditis elegans
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009141
18 Ascr#3 Caenorhabditis elegans
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009142
19 Aspartate Caenorhabditis elegans
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009140
20 Aspirin Caenorhabditis elegans, Mus musculus
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009117
21 Bezafibrate Caenorhabditis elegans
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009146
22 Blueberry polyphenols Caenorhabditis elegans
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009108
23 Blueberry polyphenols, crude Caenorhabditis elegans
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009107
24 Buformin Rattus norvegicus
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009089
25 Butylated hydroxyanisole Caenorhabditis elegans
Ageing Phenotype Observation—Data Type 2[AgeFactDB Curator icon]AgeFactDB Curator
AF_009470
26 Caffeine Saccharomyces cerevisiae
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009147
27 Carbenicillin Caenorhabditis elegans
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009143
28 Carbonylcyanide-p-trifluoromethoxyphenylhydrazone (FCCP) Caenorhabditis elegans
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009119
29 Catechin Caenorhabditis elegans
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009105
30 CCCP Caenorhabditis elegans
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009115
31 Cholesterol Caenorhabditis elegans
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009130
32 Clofibrate Caenorhabditis elegans
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009145
33 Coenzyme Q10 Caenorhabditis elegans
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009134
34 Cycloheximide Saccharomyces cerevisiae
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009063
35 Cyclosporin A Podospora anserina
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009098
36 Dafachronic acid Caenorhabditis elegans
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009076
37 Dafadine-A Caenorhabditis elegans
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009135
38 Diallyl trisulfide (DATS) Caenorhabditis elegans
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009128
39 Diazaborine Saccharomyces cerevisiae
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009064
40 Dimethyl sulfoxide Caenorhabditis elegans
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009078
41 EPEA (eicosapentaenoyl ethanolamide) Caenorhabditis elegans
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009118
42 Ethanol Saccharomyces cerevisiae
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009070
43 Ethosuximide Caenorhabditis elegans
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009091
44 FCCP Caenorhabditis elegans
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009099
45 Fenofibrate Caenorhabditis elegans
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009144
46 FUdR Caenorhabditis elegans
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009114
47 Fumarate Caenorhabditis elegans
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009137
48 Galactose Saccharomyces cerevisiae
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009106
49 Genistein Drosophila melanogaster
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009132
50 Glaucarubinone Caenorhabditis elegans
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009129
51 Glucose Candida albicans, Saccharomyces cerevisiae
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009071
52 Hydrogen peroxide diluted in S buffer Caenorhabditis elegans, Drosophila melanogaster
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009126
53 Kanamycin Caenorhabditis elegans
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009097
54 Lithocholic acid Saccharomyces cerevisiae
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009149
55 Malate Caenorhabditis elegans
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009136
56 Maltose Caenorhabditis elegans
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009085
57 Marine collagen peptides prepared from chum salmon (Oncorhynchus Rattus norvegicus
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009074
58 Metformin Caenorhabditis elegans, Mus musculus, Rattus norvegicus
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009090
59 Methanol Saccharomyces cerevisiae
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009069
60 Methionine sulfoximine Saccharomyces cerevisiae
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009061
61 Myxothiazol Caenorhabditis elegans
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009120
62 N-acetyl-cysteine Caenorhabditis elegans, Mus musculus
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
[AgeFactDB Curator icon]AgeFactDB Curator
AF_009075
63 Nicotinamide Caenorhabditis elegans, Saccharomyces cerevisiae
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009062
64 Nordihydroguaiaretic acid (NDGA) Mus musculus
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009116
65 Oxaloacetate Caenorhabditis elegans
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009100
66 Paraquat Caenorhabditis elegans
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009110
67 Phenformin Caenorhabditis elegans, Mus musculus, Rattus norvegicus
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009088
68 Phenylbutyrate Drosophila melanogaster
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009067
69 Porcine growth hormone Mus musculus
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009079
70 Quercetin Caenorhabditis elegans
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009123
71 Quercetin 3-O--d-glucopyranoside (Q3G) Caenorhabditis elegans
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009122
72 Rapamycin Mus musculus, Saccharomyces cerevisiae
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009086
73 Recombinant human IGF-1 Mus musculus
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009066
74 Reduced glutathione Caenorhabditis elegans
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009113
75 Resveratrol Mus musculus, Saccharomyces cerevisiae
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009060
76 Rutin Caenorhabditis elegans
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009124
77 Sibutramine Mus musculus, Rattus norvegicus
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009133
78 Simvastatin Mus musculus
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009087
79 Sodium chloride Saccharomyces cerevisiae
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009073
80 Sorbitol Saccharomyces cerevisiae
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009072
81 Spermidine Caenorhabditis elegans, Drosophila melanogaster, Saccharomyces cerevisiae
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009080
82 Succinate Caenorhabditis elegans
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009138
83 Succinimide Caenorhabditis elegans
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009094
84 Sucrose Caenorhabditis elegans
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009084
85 ThT (4-(3,6-dimethyl-1,3-benzothiazol-3-ium-2-yl)-N,N-dimethylan Caenorhabditis elegans
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009125
86 Trehalose Caenorhabditis elegans
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009082
87 Trimethadione Caenorhabditis elegans
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009092
88 U0126 Caenorhabditis elegans
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009148
89 Valproic acid Caenorhabditis elegans
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009095
90 Valpromide Caenorhabditis elegans
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009096
91 Vanadate Schizosaccharomyces pombe
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009077