Research Centre Information Centre AgeFactDB
Release 1 - Aug 15, 2013

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Other Ageing Factors List

NOTE:

Ageing phenotype observations are considered as experimental analysis. They confirm or reject the ageing relevance for particular ageing factor(s). For genes that are homologous to known ageing-relevant genes there is thus far no experimental evidence. They are considered as candidate genes.
Due to the different data structures of ageing phenotype observation data integrated from other databases we subdivide these observations into type 1 and 2. Observations of type 1 contain the phenotype data mostly unseparated within a single description. Observations of type 2 contain lifespan data in a more structured form (e.g.: separated into lifespan effect, lifespan change, lifespan value). Currently there might be an overlap between the observations of type 1 and 2 from the same source, namely GenAge. But we are working on a reduction of this overlap.

Ageing Relevance:
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# Other Ageing Factor Name Species Ageing Relevance Analysis Ageing Factor Stable ID
1 Agar barrier Caenorhabditis elegans
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009167
2 Alpha factor arrest Saccharomyces cerevisiae
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009155
3 Alternative carbon source Saccharomyces cerevisiae
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009183
4 Amphid sheath cell ablation Caenorhabditis elegans
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009172
5 Axenic medium Caenorhabditis elegans
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009185
6 B. subtilis food Caenorhabditis elegans
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009178
7 Caloric restriction Caenorhabditis elegans, Mus musculus
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009189
8 Diet Caenorhabditis elegans
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009204
9 Dietary deprivation Caenorhabditis elegans
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009190
10 Dietary enhancement Drosophila melanogaster
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009197
11 Dietary restriction Aedes aegypti, Caenorhabditis elegans, Caenorhabditis remanei, Ceratitis capitata, Danio rerio, Drosophila melanogaster, Mus musculus, Nothobranchius furzeri, Podospora anserina, Rattus norvegicus, Saccharomyces cerevisiae, Schizosaccharomyces pombe
Ageing Phenotype Observation—Data Type 1[GenDR icon]GenDR
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009150
12 Dietary restriction (transient) Caenorhabditis elegans
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009165
13 Dietary supplementation Caenorhabditis elegans
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
[AgeFactDB Curator icon]AgeFactDB Curator
AF_009199
14 Diploidization Saccharomyces cerevisiae
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009152
15 Environmental enrichment Mus musculus
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009171
16 ERC release Saccharomyces cerevisiae
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009154
17 Exposure to males Drosophila melanogaster
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009200
18 Farinocystis infection Euscepes postfasciatus
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009159
19 Food source Caenorhabditis elegans
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009192
20 Gender separation Nothobranchius furzeri
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009206
21 Germ cell ablation Caenorhabditis elegans
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009169
22 Heat killed bacterial food Caenorhabditis elegans
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009184
23 Heat shock Caenorhabditis elegans
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009176
24 Heat stress Caenorhabditis elegans
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009203
25 High polyamine diet Mus musculus
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009173
26 High temperature Saccharomyces cerevisiae
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009181
27 HSP-16A Caenorhabditis elegans
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009193
28 Hydrogen peroxide Drosophila melanogaster
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009198
29 Increased amino acids Saccharomyces cerevisiae
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009168
30 Intermittent feeding Mus musculus
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009202
31 Intermittent feeding plus polyphenols Mus musculus
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009201
32 Irradiation Mus musculus
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009157
33 Low polyamine diet Mus musculus
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009174
34 Low temperature Saccharomyces cerevisiae
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009182
35 Mating type conversion Saccharomyces cerevisiae
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009153
36 OP50 supernatant Caenorhabditis elegans
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009166
37 Overfeeding Caenorhabditis elegans
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009180
38 Oxidative stress Caenorhabditis elegans, Drosophila melanogaster
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009191
39 Pathogen resistance Caenorhabditis elegans
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009194
40 Petite Saccharomyces cerevisiae
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009156
41 pH 6 buffer Saccharomyces cerevisiae
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009164
42 pH 6 buffering Saccharomyces cerevisiae
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009162
43 Polyandry Drosophila pseudoobscura
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009207
44 Population enriched for 17-18 generation-old cells Saccharomyces cerevisiae
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009187
45 Population enriched for 3 generation-old cells Saccharomyces cerevisiae
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009188
46 Q-less diet Caenorhabditis elegans
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009161
47 Radiofrequency exposure Rattus norvegicus
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009160
48 Reduced oxygen Caenorhabditis elegans
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009177
49 rho0 Saccharomyces cerevisiae
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009151
50 Somatic gonad ablation Caenorhabditis elegans
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009170
51 Stachys lavandulifolia extract Drosophila melanogaster
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009158
52 Starvation Caenorhabditis elegans
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009205
53 Temperature Caenorhabditis elegans, Nothobranchius furzeri, Saccharomyces cerevisiae
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009186
54 Transfer to water Saccharomyces cerevisiae
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009163
55 UV irradiation Caenorhabditis elegans
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009196
56 UV killed food Caenorhabditis elegans
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009179
57 UV-killed diet Caenorhabditis elegans
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009195
58 UV-killed OP50 Caenorhabditis elegans
Ageing Phenotype Observation—Data Type 2[Lifespan Observations Database icon]Lifespan Observations Database
AF_009175